Ed,
I had a similar problem with my 68 280SL, and like you, I chased dirty fuel filters, clogged fuel lines, clogged vents, dirty tank, electric fuel pump, etc. The problem turned out to be the electric pump. It checked out OK--initially, so it threw me off. But apparently, after running for a few minutes, or sometimes several tens of iminutes, it would either quit or just run weak. A new short pump (with my old one as a core trade in) solved my problem. In fact, my car ran much better than it ever had before. And the problem has not reappeared in over a year. Good luck!
-Enrique Garcia