Pawel put together a list of drain holes and plugs, see here
file:///C:/Users/Bob/Downloads/Water%20drains_amended%2009_04.pdf
On my car the hole by the wiper motor is plugged, i can't see a need for a drain here, as the cowl slopes down to the engine bay, so any water should run off, not sure why there is a hole in this position?
The other hole you circled in yellow, Pawel says it's a good idea to plug, as it leads to a box section, and then to the wheel well, where the drains may be blocked
Apologies, not sure where that link came from, luckily Gary has provided the correct link