I have been playing with camshafts quite a bit, on M116/M117 engines though. In my experience, displacement does influence quite a bit the way a camshaft profile will work on an engine. For a given profile, the smaller the displacement, the more aggressive the engine behavior. Fitting a 09 camshaft on a 250 will have your engine be more aggressive than a 280 fitted with the same camshaft. Your torque and power curves may be pushed up in the rpm range by quite a bit, and you will loose some torque at lower rpm, with some consequences on driveability in town for example. One way to deal with it is to advance the timing of your camshaft by a few degrees to get your curves back a bit lower in the rpm range. Another way, especially if you like the aggressive nature of the engine, is to adapt the rear end ratio so as to get back into sufficient torque when you upshift. Nothing wrong with any of it, but you will be entering uncharted territory as you will have to adapt the timing of your camshaft to your liking, and then the injection and ignition adjustments to it. The difficulty is that standard/stock adjustments won't really apply anymore. But if you like tinkering, it's a lot of fun!