The thing I worry about just a bit, from time to time on older cars like ours, is whether the timing marks we use on the harmonic balancer/crankshaft pulley is actually in the 'spot' it is supposed to be (0 at TDC compression stroke cylinder 1, normally I think), or whether due to some mistake, timing chain stretch or what have you, it is off. Because if that is the case, naturally we are not setting the timing correct.
So, experts like Dan - would you advise us to always double check the timing marks by manually setting top dead center (spark plug out, feeler inside cylinder no. 1 with a dial indicator to tell us exactly whether the 0 mark is in the right spot)? So far, I have always relied on the timing marks being spot on, but also note that, when I finally replaced my timing chain, it did affect the running characteristics, as it moved all the components (camshaft, valves, pistons, ignition timing) closer to spec.