Welcome to the group. Having done many of the things you are proposing over a long period of time, here's my take on some of it:
1) replace or rebuild water pump (original 2 bolt serviceable unit) as it is mildly leaking from the shaft when running
These pumps tend to leak at the bearings, from sitting a while while the car isn't used. Few of our cars are used daily and this will be an issue. Probably easier to just replace it. BUT: while you are at it, since removing it can be a royal PIA, you may consider re-coring the radiator (if it has not been), and repainting/refinishing some of the parts you need to remove in order to get the water pump out. Now, I have a 280SL, USA version, but at the time I did the water pump, I had the radiator recored, changed all the radiator hoses, belts, and refinished the cowl, and air cleaner housing.
2) address a misfire/ fuel issue evident at 2500-3000 rpm
You've got some solid advice from others there. Linkage tour is one. Also before you consider adding any kind of electronic ignition, you want to ensure your distributor isn't showing signs of wear. Check all the wires and connections, points, etc. If you don't get the ignition correct before you put an electronic in, you may not fix any issues--just mask them.
3) PO had his mechanic wire a toggle switch to activate CSV, bypassing the CS relay and TTS. Will return this to original (looks like he ran new wires to solenoid so harness appears to be intact
Wondering on this, if the PO was trying to put a band aid on another issue?
4) PO had his mechanic wire a start button b/c the ignition switch stopped activating starter. Will return this to original/ replace or repair ignition switch
Yeah, replacement of the ignition switch, or repair is in serious order there...and that "fix" probably would tell me that #3 above is also a "fix".
5) replace US spec headlights with Euro (PO did this in 70's)
The PO did this in the 70s probably to get the car to pass inspection or legitimized for the USA. If you already have the parts, fine--it's a few hours work one afternoon. If not, it's a pretty costly change, so best (IMHO) to spend the money on sorting out runnability first. If it's not running right, and you have all these wacky fixes like the ignition switch bypass, you probably won't be driving much at night, so move that down the list unless you need quick gratification. I keep wanting brighter and better lights on my USA spec car until I catch myself with the fact that I don't drive at night if I can help it, and not in the rain either.
6) troubleshoot heat blower fan/ mixer controls
Hope your back is in good shape. It's a bear getting underneath where all this stuff is. Blower motors are available and you may be able to have yours repaired if that's the issue.
7) normal brake check/ chassis lube
You may be able to send the brake calipers out for a relatively inexpensive rebuild; check with a local foreign auto parts store. Change all the hoses unless you know they are new. If you want to go you need to stop!
Unless you have evidence to the contrary, assume all the hoses and belts may need a change, and certainly all the fluids do.