Regarding vapor lock, Albert is right that having a clear fuel return line is critical. The fuel system in the W113s recirculates a lot of fuel, and clears vapors out by pumping the vapors back to the fuel tank. There is, however, a little more to it than that.
The earlier cars, originally fitted with the "large" fuel pump, have a hole in the fuel overflow valve in the injection pump. This hole allows vapors to pass through, into the return line and back to the tank.
The later cars, after about mid-1969 with the later style "small" fuel pump, have a vapor bypass fitting and line from the fuel pump to the return line, and no hole in the injection pump overflow valve.
In between, some cars were fitted with the small fuel pump, but the early vapor relief system. These have the bypass fitting on the fuel pump blocked, and have the hole in the injection pump overflow valve.
If a fuel pump with no bypass is fitted to a later car that orignally had a bypass, you end up with no provision for evacuating vapors. In this case, the overflow valve with the hole in it should be installed.
Raising the fuel pressure may help reduce vapor lock, but if the fuel return line is clear and the car has one of the correct vapor relief systems, vapor lock shouldn't be a problem.
George Davis
'69 280 SL Euro manual