I am laughing at Shvegel's and GGR here...these are all absolutely identical issues, recommended solutions, questions, etc. that I dealt with. YEARS ago.
Since we (me and several mechanics and intelligent people here too that we all know and respect) were trying every possible solution EXCEPT replace the costly tank, we did it all. We checked fuel pressure and volume, we changed the filler cap, we snaked out and blew out all the fuel lines, we changed fuel filters, we cleaned screens, we checked things in the tank and on and on it went.
The beauty of what we did is I did discover one issue compounding the runnability problems, and that was a compromised electrical feed to the fuel pump. That doesn't and didn't change the tank.
When I brought the car after all this to another mechanic (who was reported to have apprenticed in Germany, and worked at Sindelfingen in the late 1960s) who knew these cars well, he heard my story, and in one
Herzschlag said "new tank". He pointed to a literal PILE of old discarded fuel tanks from Pagodas and other similar cars (250SE, 280SE, etc.) in his shop and said, "See? All similar problems. All similar solutions. Replace the tank and your problems will disappear."
I did (well, he did) and the problems went away. His claim is that after 40+ years the tank is continually rusting away from the inside, even with microscopic rust. Even if you were to be able to remove the tank, open it up, clean it out, and put it back, your problems will quickly return. I had no choice but to believe him due to respecting his experience, and the fact that we tried darn near everything else INCLUDING a new fuel pump before getting to this guy.
What I did NOT do is salvage the old tank to cut it open and really get to the bottom of what gets plugged up inside, and why it causes the issues it does. But with a fine running car, that was the least of my concerns as I drove away (cue the music) into the sunset of a fine August day...
Of course there might be disbelievers out there, and the possibility remains that the mechanic was a cad, a shyster, and what he really did was unnecessarily change my tank, AFTER tweaking the miracle, hidden screw that only he know about to fix all my problems. I honestly don't know. I do know for certain I did indeed get the new tank I paid for, and that all my problems I brought the car in for went away with the new tank. Whoosh. Just like that!
With the new fuels containing more ethanol than ever, I suspect my "new" tank will not last as long as the old tank did, which during its lifetime saw mostly fuel w/o any ethanol at all. As we all know ethanol has an affinity for water, and the water/moisture dissolved in the ethanol in the fuel accelerates the degradation of the fuel tank insides.